• Users Online: 36
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2018  |  Volume : 1  |  Issue : 1  |  Page : 2-7

Concentrated growth factors in maxillary sinus floor augmentation: A preliminary clinical comparative evaluation


1 Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio, Italy
2 Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio, Italy; Faculty of Dentistry, School of Dental Health, BPP University, London, England
3 Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio; Private Practice, Sassuolo, Italy

Correspondence Address:
Prof. Giovanna Garuti
Via del Pozzo 71, Modena
Italy
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/GFSC.GFSC_6_18

Rights and Permissions

Aims: The primary aim of this clinical study was to examine the effect of concentrated growth factors matrix (CGFm) on implant survival rate in augmented sinuses; the secondary aim was to evaluate the effect of CGFm on sinus augmentation postoperative morbidity. Materials and Methods: Fifty patients were selected from a pool of participants requiring maxillary sinus augmentation. Of these, 25 patients (control-group) received a corticocancellous xenograft. The other 25 patients (test group) received a mixture of 70% CGF matrix and 30% corticocancellous xenograft. Venous blood samples were drawn from each patient and immediately centrifuged. Four components were identified vertically from top to bottom: (1) An upper liquid phase constituted by serum; (2) a phase constituted by polymerized fibrin buffy coat; (3) a middle phase constituted by aggregated platelets with CGFs; and (4) a lower phase constituted by red blood cells. The middle (second and third) phases represented the CGFm and were mixed with the graft material. The survival rate was calculated and comparison was made between the 2 different groups using Kaplan–Meier analysis. Statistical significance was set at P < 0.05. Results: A 96.4% survival rate was described in the test group (with CGFm) and a 96.1% survival rate in the control group (without CGFm). No statistically significant differences were observed between the survival rates of the two groups after 1 year. Conclusions: The mixture of CGFm (70%) with xenograft (30%) is an alternative to xenograft material alone and is a predictable procedure resulting in less postoperative morbidity in sinus augmentation.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed542    
    Printed22    
    Emailed0    
    PDF Downloaded257    
    Comments [Add]    

Recommend this journal