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Table of Contents
Year : 2018  |  Volume : 1  |  Issue : 1  |  Page : 1

Regenerative medicine 4.0

Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy

Date of Web Publication13-Apr-2018

Correspondence Address:
Prof. Adriano Piattelli
Department of Medical, Oral and Biotechnological Sciences, Dental School, University of Chieti-Pescara, Chieti
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/GFSC.GFSC_8_18

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How to cite this article:
Piattelli A. Regenerative medicine 4.0. Int J Growth Factors Stem Cells Dent 2018;1:1

How to cite this URL:
Piattelli A. Regenerative medicine 4.0. Int J Growth Factors Stem Cells Dent [serial online] 2018 [cited 2023 Oct 3];1:1. Available from: https://www.cellsindentistry.org/text.asp?2018/1/1/1/230073

The mission of regenerative medicine is to repair, restore, or replace damaged or diseased cells, tissues, or organs. This approach, which is eminently and truly interdisciplinary, spanning tissue engineering, gene therapy, biomaterials, growth factors, nanotechnology, transplantation science, cell therapy, and developmental cell biology, probably will create a revolution in patient care in the not so distant future. Regenerative Medicine comprises a multifaceted field, involving many different techniques. Cells and tissues could be transplanted, cells could be used as a vehicle for the delivery of agents, treatments stimulating the repair processes of the human body could be performed. All or most of these techniques will, probably, make possible to treat previously untreatable diseases and injuries and also to meet the needs of an aging population all over the world. The main challenge will be to transfer several promising discoveries in basic science toward the clinical setting and practice. There is a need for a high-level research base, a well-organized infrastructure to support the scientific developments, the knowledge useful for an experimental validation of different approaches and techniques, so as to make it possible to translate data from research to clinical settings and applications. The key will be to better understand the body regenerative processes. We have to understand, e.g., how a transplanted cell will behave over time in a host tissue, taking into consideration the fact that regeneration sites are usually hostile environments, and in some cases, the transplanted cells are not able to work, or to understand how a correct cell signal could stimulate tissue repair. Pluripotent stem cells will play a pivotal role in many of the fields of Regenerative Medicine, but we have to further characterize these cells, to evaluate their stability over time, with a quality control that could guarantee a complete safety and reproducibility of the procedures.

For all these reasons, the recent appearance of a new international journal dedicated to these topics, the International Journal of Growth Factors and Stem Cells in Dentistry, is timely and warranted.

We have to commend the efforts of Prof. Carlos Mourao, who is the driving force behind this new, exciting adventure.


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